研究者・留学生向け英文メールニュース「Tokyo Tech Bulletin No. 64」を配信

A research team, led by Professor Saburo Matunaga, School of Engineering Tokyo Tech, developed a 50 kg class technology demonstration microsatellite called HIBARI that denotes "skylark" in English. The purpose of this satellite is the on-orbit demonstration of Variable Shape Attitude Control (VSAC) technology where attitude and orbit are controlled using a variable structure, and the satellite adjusts the attitude via the recoil from the movement of the four movable solar cell paddles. By deploying and retracting the paddles, atmospheric drag can be adjusted and used for orbit control.

DNA capsules with changing patterns and ability of enzymatic reactions could pave the way for artificial cells and molecular robots. Biophysicists in Japan have found ways to make and manipulate capsule-like DNA structures that could be used in the development of artificial molecular systems. Such systems could function, for example, inside the human body. The study was a collaboration between Yusuke Sato of Tohoku University and Masahiro Takinoue of Tokyo Tech and the findings were published in the JACS Au.

The molecular mechanism underlying enzyme activity regulation of ubiquitin-specific protease 8 (USP8) has been decoded by researchers at Tokyo Tech. USP8 has been implicated in Cushing's disease pathogenesis. They identified an autoinhibitory region on the enzyme that interacts with its catalytic region. They also provide first evidence on the release of autoinhibition due to USP8 mutations as the underlying cause behind Cushing's disease. Their findings could be invaluable for understanding Cushing's disease pathogenesis.

Using photocatalysts to reduce CO₂ has received a lot of attention recently. Scientists from Tokyo Tech have developed a new osmium complex that can absorb a full wavelength range of visible light and act as a panchromatic redox photosensitizer for CO₂ reduction. The team combined this complex with a ruthenium (II) catalyst and successfully reduced CO₂ into formic acid.

Protein assembly is essential for the formation of ordered biological structures, but imagine engineering one! This is exactly what researchers at Tokyo Tech have now accomplished with protein needles. By regulating the tip-to-tip interactions of these needles, they allowed for their self-assembly into lattice structures, ordered monomeric states, and fiber assemblies, paving the way for the controlled construction of more of such protein architectures.

All-solid-state batteries are now one step closer to becoming the powerhouse of next-generation electronics as researchers from Tokyo Tech, AIST, and Yamagata University introduce a strategy to restore their low electrical resistance. They also explore the underlying reduction mechanism, paving the way for a more fundamental understanding of the workings of all-solid-state lithium batteries.

A new organic peroxide molecule, BMPF, prepared by scientists at Tokyo Institute of Technology (Tokyo Tech), releases fluorescence under mechanical stress and could be incorporated into polymer networks for mechanofunctional design. BMPF-linked polymers are also stable at relatively high temperatures and could pave the way for highly selective and efficient small-molecule-releasing systems with applications in imaging and drug delivery.

Protein production (translation) is a complex process involving machinery called ribosomes. How do cells counter ribosomal destabilization leading to premature termination of translation? Scientists at Tokyo Institute of Technology (Tokyo Tech) uncover a novel role of nascent protein chains in stabilizing translating ribosomes. They suggest that longer peptide sequences spanning the ribosomal exit tunnel and bulky amino acid residues in the tunnel entry help stabilize the ribosome by bridging its subunits, ensuring uninterrupted translation.